Allergen Components have a wide variety of uses - from the diagnosis and management of allergic patients to the selection of patients suitable for Specific Immunotherapy. Use of Component Resolved Diagnostics (CRD) has fast become an interesting and probably essential part of allergy diagnostics. Allergens, such as a species of pollen, a mite or a food are composed of a number of different 'potential' allergenic molecules that may cause sensitisation. A much more precise and detailed picture of the patient's sensitisation pattern can be obtained by measuring IgE to the components. This gives more information for the management of an allergen-sensitised individual indicating whether, for example, symptoms are likely to be severe and ultimately leads to better patient care.

COMPONENTS - click to go to component
Alternaria  |  Aspergillus  |  Birch  |  Brazil  |  Cat  |  Celery  |  Cow's Milk  |  Dog
Egg  |  Fish  |  Hazelnut  |  House Dust Mite  |  Kiwi  |  Latex  |  Olive  |  Peach
Peanut  |  Shrimp  |  Soybean  |  Tomothy Glass  |  Venom  |  Wall Pellitory  |  Wheat

PROTEINS - click to go to protein
PR-10 |  Lipid Transfer  |  Profilins  |  Polcalcins  |  Seed Storage
Glycan Determinants  |  Lipocalins  | Parvalbumins  |  Serum Albumins | Tropomyosins
 

 

ALTERNARIA COMPONENTS

All tests can be requested individually
m6
m229 
Alternaria alternata
rAlta1 
second section
ZZ1  

 

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ASPERGILLUS COMPONENTS

Aspergillus fumigatus allergen components
m3
m218
m219
m220
m221
m222 
Aspergillus fumigatus
rAsp f1
rAsp f2
rAsp f3
rAsp f4
rAsp f6
 
ZZ2  

 

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BIRCH COMPONENTS

Birch allergen components (Betula verrucosa)
t3
t215
t216
t220
t225 
Betula verrucosa (Silver Birch)
rBet v 1
rBet v 2
rBet v 4
rBet v 6
 
PR-10
Profilin
Ca binding protein

 
ZZ3  

 

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BRAZIL COMPONENTS

Brazil allergen components (Bertholletia excelsa)
f18
f354 
Brazil Nut
rBer e 1 
Storage protein 2S albumin
 
ZZ4  

 

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CAT COMPONENTS

Cat allergen components (Felis domesticus)
e1
e94
e220 
Cat
rFel d 1
nFel d 2 
Cat dander
Uteroglobulin
Serum Albumin 
ZZ5  

 

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CELERY COMPONENTS

Celery allergen components (Apium graveolens)
f85
f417
m229 
Celery
rApi g 1.01 
PR-10
ZZ6  

 

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COW'S MILK COMPONENTS

Cow's milk allergen components (Bos domesticus)
f2
f76
f77
e204
f78
f334 
Milk
nBos d 4 
nBos d 5
nBos d 6
nBos d 8
nBos d lactoferrin
 
a-lactalbumin
b-lactoglobulin
BSA cow
Casein milk
Lactoferrin
 
ZZ7  

 

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DOG COMPONENTS

Dog allergen components (Canis familiaris)
e5
e101
e102
e221 
Dog
rCan f 1
rCan f 2
nCan f3 
Dog dander
Lipocalin
Lipocalin
Serum Albumin 
ZZ8 

 

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EGG COMPONENTS

Egg allergen components (Gallus domesticus)
f1
f75
f233
f232
f323
k208 
egg white
egg yolk
nGal d 1
nGal d 2
nGal d 3
nGal d 4
Ovomucoid
Ovalbumin
Conalbumin
Lysozyme

 
ZZ9  

 

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FISH COMPONENTS

Fish Allergen
Carp allergen components (Cyprinus carpio)
Cod allergen component (Gadus morhua) 
f3
f355
f426 
Cod
rCyp c 1
rGad c 1 
Parvalbumin
Parvalbumin
 
ZZ10  

 

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HAZELNUT COMPONENTS

Hazel Components (Corylus avellana)
f17
f428
f425 
Hazel Nut
rCor a 1
rCor a 8 
PR-10
LTP
 
ZZ11  

 

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HOUSE DUST MITE COMPONENT

House Dust Mite (Dermatophagoides pteronyssinus)
d1
d202
d203
d205 
House Dust Mite
nDer p 1
rDer p 2
rDer p 10 
Tropomyosin


 
ZZ12  

 

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KIWI COMPONENTS

Kiwi components (Actinidia deliciosa)
f84
f430 
Kiwi
rAct d 8 
PR10
 
ZZ32

 

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LATEX COMPONENTS

Latex allergen components (Hevea brasiliensis)
k82
k215
k217
k218
k219
k220
k221
k222
k224 
Latex
rHev b 1
rHev b 3
rHev b 5
rHev b 6.01
rHev b 6.02
rHev b 8
rHev b 9
rHev b 11
 
Profilin







 
ZZ13  

 

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OLIVE COMPONENTS

Olive allergen components (Olea europaea)
t9
t224 
Olive
nOle e 1 
 
ZZ14  

 

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PEACH COMPONENTS

Peach allergen components (Prunus persica)
f95
f419
f420
f421 
Peach
rPru p 1
rPru p 3
rPru p 4 
PR-10
LTP
Profilin
 
ZZ15  

 

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PEANUT COMPONENTS

Peanut allergen components (Arachis hypogea)
f13
f422
f423
f424
f352
f427 
Peanut
rAra h 1
rAra h 2
rAra h 3 
rAra h 8
rAra h 9
 
7S globulins
2S albumins
11S globulin
PR-10
LTP
 
ZZ16  

 

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SHRIMP COMPONENTS

Shrimp allergen components (Penaeus aztecus)
k24
f351 
Alternaria alternata
rAlta1 
second section
ZZ17  

 

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SOYBEAN COMPONENTS

Soybean allergen components (Glycin max)
f14
f353
f431
f432   
Soya
rGly m 4
nGly m 5
nGly m 6 
PR-10
beta-conglycinin
glycinin
 
ZZ18 

 

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TIMOTHY GRASS COMPONENTS

Timothy grass allergen components (Phelum pratense)
g6
g205
g206
g208
g215
g209
g210
g211
g212
Timothy
rPhl p 1 
rPhl p 2 
rPhl p 4 
rPhl p 5b 
rPhl p 6
rPhl p 7 
rPhl p 11 
rPhl p 12 
 
Grass Group 1
Grass Group 2
Grass Group 5

Ca Binding Protein

Profilin

 
ZZ19 

 

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VENOM COMPONENTS

Proteins found in insect venoms. Specific markers particularly important when considering venom immunisation
Venoms
l208
l210
l209
i211
 
rApi m 1
rPol d 5
rVes v 5
rVes v 1
 
Phospholipase A2, Honey Bee
European Paper Wasp
Common wasp
Phospholipase A1, Common Wasp
ZZ33 

 

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WALL PELLITORY COMPONENTS

Wall pellitory allergen components (Parietaria judaica)
w21
w211
Wall Pellitory
rPar j 2
LTP
 
ZZ20 

 

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WHEAT COMPONENTS

Wheat allergen components (Triticum aestivum)
f4
f416 
Wheat
rTri a 19 
Omega-5 Gliadin
 
ZZ21  

 

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PR-10 PROTEINS

PR-10 Proteins
t215
f428
f419
f353
f352
f417
f430
rBet v 1
rCor a 1
rPru p 1
rGly m 4
rAra h 8
rApi g 1.01
rAct d 8
PR-10
PR-10
PR-10
PR-10
PR-10
PR-10
PR-10
 
A heat labile protein, cooked foods are often tolerated.
Often associated with local symptoms such as Oral AllergySyndrome (OAS).
Often associated with allergic reactions to fruit and vegetables in Northern Europe. 
 ZZ22 

 

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LIPID TRANSFER PROTEINS

Lipid transfer proteins
f420
f425
f427
w211 
rPru p 3
rCor a 8
rAra h 9
rPar j 2 
LTP
LTP 
LTP
LTP 
A stable protein to heat and digestion causing reactions to cooked foods.
Often associated with systemic and more severe reactions in addition to OAS
Often associated with allergic reactions to fruit and vegetables in Southern Europe. 
 ZZ23  

 

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PROFILINS

Profilins
t216
t421
g212
k221 
rBet v 2
rPru p 4
rPhl p 12
rHev b 8 
Profilin
Profilin 
Profilin 
Profilin 
 
Seldom associated with clinical symptoms but may cause demonstrable or even severe reactions in a small minority of cases.
 ZZ24 

 

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POLCALCINS

Polcalcins
t220
g210 
rBet v 4
rPhl p 7 
ca binding protein
ca binding protein 
 ZZ25  

 

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SEED STORAGE PROTEINS

Seed storage proteins
f423
f354
f431
f432
f422
f424
f416 
rAra h 2
rBer e 1
nGly m 5
nGly m 6
rAra h 1
rAra h 3
rTri a 19 
2S albumins
2S albumins
beta-glycinin
glycinin
7S globulins
11S globulin
Omega-5 Gliadin 
Protein found in seeds serving as source material during growth of new plant.
Often stable and heat resistant  
 ZZ26  

 

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GLYCAN DETERMINANTS

Glycan determinants
o214 MUXF3 CCD Bromelin
A marker for sensitisation to cross reactive-reactivity between species.
Seldom associated with clinical symptoms but may cause demonstrable or even severe reactions in a small minority of patients. 
 ZZ27  

 

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LIPOCALINS

Lipocalins
e101
e102 
rCan f 1
rCan f 2 
Lipocalin
Lipocalin 
Very stable proteins. Allergen components displaying limited cross-reactivity between species.
 ZZ28  

 

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PARVALBUMINS

Parvalbumins
f355
f426 
rCyp c 1 (Carp)
rGad c 1 (Cod) 
Parvalbumin
Parvalbumin 
A major allergen in fish. A marker for cross-reactivity among different species of fish and amphibians.
A protein stable to heat and digestion causing reactions to cooked foods. 
 ZZ29  

 

B

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SERUM ALBUMINS

Serum albumins
e204
e220
e221
e222 
nBos d 6
nFel d 2
nCan f 3
nSus s 
Serum Albumin cow
Serum Albumin cat
Serum Albumin dog
Serum Albumin pig 
A common protein present in different biological fluids and solids.
Cross-reactions between albumins from different animal species are well known for example between cat, dog, cow and pork. 
 ZZ30  

 

B

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TROPOMYOSINS

Tropomyosins
f351
d205 
rPen a 1
rDer p 10 
Tropomyosin
Tropomyosin 
An actin-binding protein in muscle fibres.
A marker for cross-reactivity between crustaceans, mites and cockroaches. 
 ZZ31  

 

B

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